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7 - Plasmonic biosensing devices and systems

Published online by Cambridge University Press:  05 March 2014

Er-Ping Li  and
Hong-Son Chu
Er-Ping Li
Affiliation:
A*STAR Institute of High Performance Computing, Singapore
Hong-Son Chu
Affiliation:
A*STAR Institute of High Performance Computing, Singapore
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Summary

To detect an analyte, surface plasmons whose characteristics are sensitive to the refractive-index variations close to the sensor's surface are excited and measured. Binding of the target analyte onto the sensor's surface will cause changes in refractive index and hence in the measured plasmonic characteristics. Depending on what type of surface plasmon is excited (e.g. surface plasmon polariton (SPP), Fano resonance), which plasmonic characteristic is measured/modulated (e.g. resonance wavelength, transmitted light intensity), and in what manner the bio-functionalization (i.e. binding of the target analyte) is performed, there are many different configurations for plasmonic biosensors, which will be reviewed in this chapter. The ultimate goal is to increase the sensor's sensitivity and the figure of merit. To achieve this goal, one must first understand the physics of the resonances, and then implement a smart structural design. In this chapter, two design methods will be introduced: an N-layer model and a finite-element-method (FEM) model, which are further elaborated by presentation of three biosensor design examples.

Introduction

A biosensor is a device for detecting an analyte, which typically combines a biological component with a physiochemical detector. For instance, a blood-glucose biosensor uses the enzyme glucose oxidase to break blood glucose down. In doing so it first oxidizes glucose and uses two electrons to reduce the FAD (a component of the enzyme) to FADH2. Then the FADH2 is oxidized by accepting two electrons from the electrode.

Type
Chapter
Information
Plasmonic Nanoelectronics and Sensing , pp. 217 - 248
Publisher: Cambridge University Press
Print publication year: 2014

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References

[1] S. A., Maier, Plasmonics: Fundamentals and Applications. Berlin: Springer, 2007.
[2] J., Homola, “Present and future of surface plasmon resonance biosensors,” Anal. Bioanal. Chem., vol. 377, pp. 528–539, 2003.Google Scholar
[3] I., Abdulhalim, M., Zourob, and A., Lakhtakia, “Surface plasmon resonance for biosensing: A mini-review,” Electromagnetics, vol. 28, pp. 214–242, 2008.Google Scholar
[4] J. N., Anker, W. P., Hall, O., Lyanderset al., “Biosensing with plasmonic nanosensors,” Nature Mater., vol. 7, pp. 442–453, 2008.Google Scholar
[5] M. E., Stewart, C. R., Anderton, L. B., Thompsonet al., “Nanostructured plasmonic sensors,” Chem. Rev., vol. 108, pp. 494–521, 2008.Google Scholar
[6] B., Sepúlveda, P. C., Angelomé, L. M., Lechuga, and L. M., Liz-Marzán, “LSPR-based nanobiosensors,” Nano Today, vol. 4, pp. 244–251, 2009.Google Scholar
[7] T. W., Ebbesen, H. J., Lezec, H. F., Ghaemi, T., Thio, and P. A., Wolff, “Extraordinary optical transmission through sub-wavelength hole arrays,” Nature, vol. 391, pp. 667–669, 1998.Google Scholar
[8] H. F., Ghaemi, T., Thio, D. E., Grupp, T. W., Ebbesen, and H. J., Lezec, “Surface plasmons enhance optical transmission through subwavelength holes,” Phys. Rev. B, vol. 58, pp. 6779–6782, 1998.Google Scholar
[9] A., Degiron, H. J., Lezec, W. L., Barnes, and T. W., Ebbesen, “Effects of hole depth on enhanced light transmission through subwavelength hole arrays,” Appl. Phys. Lett., vol. 81, pp. 4327–4329, 2002.Google Scholar
[10] W. L., Barnes, W. A., Murray, J., Dintinger, E., Devaux, and T. W., Ebbesen, “Surface plasmon polaritons and their role in the enhanced transmission of light through periodic arrays of subwavelength holes in a metal film,” Phys. Rev. Lett., vol. 92, 107401, 2004.Google Scholar
[11] J., Prikulis, P., Hanarp, L., Olofsson, D., Sutherland, and M., Kall, “Optical spectroscopy of nanometric holes in thin gold films,” Nano Lett., vol. 4, pp. 1003–1007, 2004.Google Scholar
[12] H. J., Lezec and T., Thio, “Diffracted evanescent wave model for enhanced and suppressed optical transmission through subwavelength hole arrays,” Opt. Express, vol. 12, pp. 3629–3651, 2004.Google Scholar
[13] A., DegironandT. W., Ebbesen, “The role of localized surface plasmon modes in the enhanced transmission of periodic subwavelength apertures,” J. Opt. A: PureAppl. Opt., vol. 7, pp. S90–S96, 2005.Google Scholar
[14] C., Genet and T. W., Ebbesen, “Light in tiny holes,” Nature, vol. 445, pp. 39–46, 2007.Google Scholar
[15] F. J., Garcia-Vidal, L., Martin-Moreno, T. W., Ebbesen, and L., Kuipers, “Light passing through subwavelength apertures,” Rev. Mod. Phys., vol. 82, pp. 729–787, 2010.Google Scholar
[16] T., Sannomiya, O., Scholder, K., Jefimovs, C., Hafner, and A. B., Dahlin, “Investigation of plasmon resonances in metal films with nanohole arrays for biosensing applications,” Small, vol. 7, pp. 1653–1663, 2011.Google Scholar
[17] K.-L., Lee, C.-W., Lee, W.-S., Wang, and P.-K., Wei, “Sensitive biosensor array using surface plasmon resonance on metallic nanoslits,” J. Biomed. Opt., vol. 12, 044023, 2007.Google Scholar
[18] N., Liu, T., Weiss, M., Meschet al., “Planar metamaterial analogue of electromagnetically induced transparency for plasmonic sensing,” Nano Lett., vol. 10, pp. 1103–1107, 2010.Google Scholar
[19] P., Offermans, M. C., Schaafsma, S. R. K., Rodriguezet al., “Universal scaling of the figure of merit of plasmonic sensors,” ACS Nano, vol. 5, pp. 5151–5157, 2011.Google Scholar
[20] Z., Fang, J., Cai, Z., Yanet al., “Removing a wedge from a metallic nanodisk reveals a Fano resonance,” Nano Lett., vol. 11, pp. 4475–4479, 2011.Google Scholar
[21] W.-S., Chang, J. B., Lassiter, P., Swanglapet al., “A plasmonic Fano switch,” Nano Lett., vol. 12, pp. 4977–4982, 2012.Google Scholar
[22] Y., Wang, A., Brunsen, U., Jonas, J., Dostlek, and W., Knoll, “Prostate specific antigen biosensor based on long range surface plasmon-enhanced fluorescence spectroscopy and dextran hydrogel binding matrix,” Anal. Chem., vol. 81, pp. 9625–9632, 2009.Google Scholar
[23] X. F., Li and S. F., Yu, “Extremely high sensitive plasmonic refractive index sensors based on metallic grating,” Plasmonics, vol. 5, pp. 389–394, 2010.Google Scholar
[24] M. J., Levene, J., Korlach, S. W., Turneret al., “Zero-mode waveguides for single-molecule analysis at high concentrations,” Science, vol. 299, pp. 682–686, 2003.Google Scholar
[25] F., Eftekhari, C., Escobedo, J., Ferreiraet al., “Nanoholes as nanochannels: Flow-through plasmonic sensing,” Anal. Chem., vol. 81, pp. 4308–4311, 2009.Google Scholar
[26] A. A., Yanik, M., Huang, A., Artar, T. Y., Chang, and H., Altug, “Integrated nanoplasmonic–nanofluidic biosensors with targeted delivery of analytes,” Appl. Phys. Lett., vol. 96, 021101, 2010.Google Scholar
[27] M., Yamamoto, “Surface plasmon resonance (SPR) theory: Tutorial,” Rev. Polarography, vol. 48, pp. 209–237, 2002.Google Scholar
[28] L., Wu, P., Bai, and E. P., Li, “Designing surface plasmon resonance of subwavelength hole arrays by studying absorption,” J. Opt. Soc. Am. B, vol. 29, pp. 521–528, 2012.Google Scholar
[29] E. D., Palik, Ed., Handbook of Optical Constants of Solids. San Diego, CA: Academic Press, 1991.
[30] L., Wu, H. S., Chu, W. S., Koh, and E. P., Li, “Highly sensitive graphene biosensors based on surface plasmon resonance,” Opt. Express, vol. 18, pp. 14395–14400, 2010.Google Scholar
[31] B., Song, D., Li, W. P., Qiet al., “Graphene on Au(111): A highly conductive material with excellent adsorption properties for high-resolution bio/nanodetection and identification,” ChemPhysChem, vol. 11, pp. 585–589, 2010.Google Scholar
[32] G. B., McGaughey, M., Gagné, and A. K., Rappé, “π-Stacking interactions alive and well in proteins,” J. Biol. Chem., vol. 273, pp. 15458–15463, 1998.Google Scholar
[33] Z., Tang, H., Wu, J. R., Cortet al., “Constraint of DNA on functionalized graphene improves its biostability and specificity,” Small, vol. 6, pp. 1205–1209, 2010.Google Scholar
[34] M., Bruna and S., Borinia, “Optical constants of graphene layers in the visible range,” Appl. Phys. Lett., vol. 94, 031901, 2009.Google Scholar
[35] L., Wu, P., Bai, X., Zhou, and E. P., Li, “Reflection and transmission modes in nanohole-array-based plasmonic sensors,” IEEE Photon. J., vol. 3, pp. 441–149, 2012.Google Scholar
[36] A. A., Yanik, M., Huang, O., Kamoharaet al., “An optofluidic nanoplasmonic biosensor for direct detection of live viruses from biological media,” Nano Lett., vol. 10, pp. 4962–4969, 2010.Google Scholar
[37] B., Hapke, Theory of Reflectance and Emittance Spectroscopy. Cambridge: Cambridge University Press, 1993.

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