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The Neuropathology of Dementia
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Details

  • 163 b/w illus. 106 colour illus.
  • Page extent: 584 pages
  • Size: 276 x 219 mm
  • Weight: 2.038 kg

Library of Congress

  • Dewey number: 616.8/3
  • Dewey version: 21
  • LC Classification: RC521 .N475 2004
  • LC Subject headings:
    • Dementia--Pathogenesis
    • Postmortem changes
    • Autopsy
    • Dementia--etiology
    • Dementia--pathology

Library of Congress Record

Hardback

 (ISBN-13: 9780521819152 | ISBN-10: 0521819156)

Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: • Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. • Two chapters on tauopathies under new authorship. • A chapter under new authorship on synucleinopathies, which includes multiple system atrophy. From reviews of the first edition: 'This up-to-date and authoritative account will be invaluable for practising neuropathologists and a treasured work of reference for psychiatrists and neuroscientists with an interest in dementia.' Nigel J. Cairns, International Journal of Geriatric Psychiatry ' ... this publication is a 'must have' for every practising neuropathologist.' Journal of Neuropathology and Experimental Neurology

• Completely rewritten and updated new edition of a highly successful book • International team of top-notch experts covering comprehensively all aspects of the neuropathology of dementia • Gives practical guidance for practising pathologists

Contents

Preface; 1. Definition, clinical features and neuroanatomical basis of dementia Thomas J. Grabowski and Antonio R. Damasio; 2. Important anatomical landmarks in the brain in dementia James H. Morris and Margaret M. Esiri; 3. Practical approach to pathological diagnosis Margaret M. Esiri and James H. Morris; 4. Morphometric methods and dementia Michael C. Irizarry; 5. Safety precautions in laboratories involved with dementia diagnosis and research Jeanne E. Bell; 6. Molecular diagnosis of dementia Vivianna M. D. Van Deerlin; 7. Neuropathology of the aging brain Patrick R. Hof, Thierry Bussière and John H. Morrison; 8. Neuroimaging Alzheimer's disease Arthur W. Toga, Michael S. Mega and Paul M. Thompson; 9. Alzheimer's disease James H. Morris and Zs Nagy; 10. Down's syndrome and Alzheimer's disease D. M. A. Mann; 11. Sporadic tauopathies: Pick's disease, corticobasal degeneration, progressive supranuclear palsy and argyrophilic brain disease Dennis W. Dickson; 12. Hereditary tauopathies and idiopathic frontotemporal dementias Mark S. Forman, John Q. Trojanowski and Virginia M.-Y. Lee; 13. Vascular dementias James H. Morris, Hannu Kalimo and Matti Viitanen; 14. Familial and sporadic cerebral amyloid angiopathies associated with dementia and the BRI dementias Gordon T. Plant, Tamas Revesz, Janice L. Holton, Jorge Ghiso and Blas Frangione; 15. Parkinson's disease, dementia with Lewy bodies, multiple system atrophy and the spectrum of diseases with alpha-synuclein inclusions Benoit I. Giasson, Virginia M-Y. Lee and John Q. Trojanowski; 16. Huntington disease Jean Paul G. Vonsattel and Maxim Lianski; 17. Human prion diseases James W. Ironside and Mark W. Head; 18. Alcoholism and dementia Clive Harper and Richard Scolyer; 19. Hydrocephalus and dementia Margaret M. Esiri and G. Rosenberg; 20. Head injury and dementia C. Smith, J. A. R. Nicoll and D. I. Graham; 21. Infectious (and inflammatory) diseases causing dementia Harry V. Vinters; 22. Schizophrenia and dementia Paul J. Harrison; 23. Other diseases that cause dementia Margaret M. Esiri; 24. Transgenic mouse models of neurodegenerative disease David R. Borchelt, Joanna Jankowsky, Alena Savonenko, Gabriele Schilling, Jiou Wang and Guilian Xu; Appendix: Dementia brain banks; Index.

Reviews

From reviews of the first edition: 'This up-to-date and authoritative account will be invaluable for practising neuropathologists and a treasured work of reference for psychiatrists and neuroscientists with an interest in dementia.' International Journal of Geriatric Psychiatry

'It should undoubtedly be on the shelves of consultant histopathologists in a teaching hospital … I am delighted to have a copy and have already consulted it with more enthusiasm than I would have believed possible.' Journal of the Royal Society of Medicine

'… this is certainly a compulsory purchase for neuroscience centres. It deserves to live on into further editions whose evolution will map the rapid advances being made in many of the conditions covered within.' Neuroradiology

'… this publication is a 'must have' for every practising neuropathologist.' Journal of Neuropathology and Experimental Neurology

'Esiri and Morris have succeeded in producing a book tha is informative, entertaining to read and reasonably priced to boot ... this book deserves success.' Brain

'… this work is greater than the sum of its excellent parts.' Journal of the Royal Society of Medicine '… the book fulfills its stated goal of reaching pathologists as well as workers in other disciplines who may be interested in the pathological basis of dementia. Most academically active neuropathologists will be conversant with the material, but this book will be a valuable resource for those neuroscientists and clinicians who may not have grasped the range of pathological conditions that can underlie such a complex disease.' Journal of Neurosurgery

'This authoritative and comprehensive book is one of those 'must have' books and it will be invaluable for practising neuropathologists, as well as gerontologists, neurobiologists and psychiatrists working in the field of dementia. I must admit that I am delighted to have a copy of this book and have used it with more enthusiasm that I have ever thought possible.' The Bulletin of the Royal College of Pathologists

'… offers valuable information to anyone interested or working in other neuroscience specialities. … it is a reference volume which belongs in all well-stocked institutional libraries'. Neuroradiology

'The second edition of this book, in my view, is an essential purchase for anyone entrusted with the accurate pathological diagnosis of a case of dementia.' Journal of Neurology

'This authoritative and comprehensive book is one of those 'must have' books and it will be invaluable for practising neuropathologists, as well as gerontologists, neurobiologists and psychiatrists working in the field of dementia.' The Bulletin of The Royal College of Pathologists

'A good book should fulfil at least three criteria: be of contemporary significance, be readable and have relevance to a large number of ideas and issues. The second edition of The Neuropathology of Dementia fulfils all these criteria … as an excellent neuropathological compendium and reference tool … as a starting point for anyone embarking on dementia research.' Psychological Medicine

'Verdict: obviously a must for neuropathologists with an interest in dementia …' Advances in Clinical Neuroscience and Rehabilitation

Contributors

Thomas J. Grabowski, Antonio R. Damasio, James H. Morris, Margaret M. Esiri, Michael C. Irizarry, Jeanne E. Bell, Vivianna M. D. Van Deerlin, Patrick R. Hof, Thierry Bussière, John H. Morrison, Arthur W. Toga, Michael S. Mega, Paul M. Thompson, Zs Nagy, D. M. A. Mann, Dennis W. Dickson, Mark S. Forman, John Q. Trojanowski, Virginia M.-Y. Lee, Hannu Kalimo, Matti Viitanen, Gordon T. Plant, Tamas Revesz, Janice L. Holton, Jorge Ghiso, Blas Frangione, Benoit I. Giasson, Jean Paul G. Vonsattel, Maxim Lianski, James W. Ironside, Mark W. Head, Clive Harper, Richard Scolyer, G. Rosenberg, C. Smith, J. A. R. Nicoll, D. I. Graham, Harry V. Vinters, Paul J. Harrison, David R. Borchelt, Joanna Jankowsky, Alena Savonenko, Gabriele Schilling, Jiou Wang, Guilian Xu

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