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An Introduction to Vascular Biology
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  • 90 b/w illus. 25 tables
  • Page extent: 0 pages

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 (ISBN-13: 9780511056833 | ISBN-10: 0511056834)

Vascular biology is an exciting and rapidly advancing area of medical research, with many new and emerging pathophysiological links to an increasing number of diseases. This updated and expanded new edition takes full account of these developments and conveys the basic science underlying a wide range of clinical conditions including atherosclerosis, hypertension, diabetes, and pregnancy. As with the first edition, the publication provides an introductory account of vascular biology before leading on to explain mechanisms involved in disease processes. Other emerging topics include the role of nitric oxide and apoptosis in vascular biology. The breadth and range of subjects covered in this new edition do full justice to this increasingly important area of clinical research and medicine. This multidisciplinary approach will suit the needs of all those seeking to refresh their knowledge with the very latest advances from basic science through to clinical practice.

• Fully expanded and updated with the very latest developments in the field • Uses a multidisciplinary approach to the subject • Vascular biology is at the forefront of much medical research, with links to many diseases


Part I. Basic Science: 1. Control of vascular smooth muscle contractility A. Hughes; 2. Vascular compliance Phillip Chowienczyk; 3. Flow-mediated responses L. Poston; 4. Neurohumoral regulation of vascular tone Kirsty M. McCulloch and J. C. McGrath; 5. Angiogenesis A. Halliday; 6. Apoptosis M. Bennett; 7. Wound healing N. L. Occleston and P. T. Khaw; Part II. Pathophysiology: Mechanisms and Imaging: 8. Genetics of cardiovascular disease M. J. Caulfield; 9. The endothelium in disease B. J. Hunt and J. M. Jurd; 10. Nitric oxide Patrick Vallance; 11. Imaging the vasculature Alan Moody; Part III. Clinical Practice: 12. Vascular biology in hypertension M. Schachter; 13. Atherosclerosis Peter Weissberg; 14. Aneurysms Janet Powell; 15. The vasculature in diabetes John Tooke; 16. The vasculitides Caroline Savage; 17. Pulmonary hypertension T. Higgenbottam; 18. The endothelium in transplantation M. Rose; 19. The vasculature in pregnancy L. Poston.


'Beverley Hunt and her co-editors have succeeded in putting together a collection of varied chapters in which the underlying structural and functional abnormalities in blood vessels are described scientifically in the context of clinical disorders. Individual chapters are easy to read and should provide helpful guidance to clinicians and those interested in the pathophysiological basis of vascular medicine.' Journal of the Royal Society of Medicine

Review of first edition '… it makes excellent reading … for readers who are interested in gaining fundamental understanding of this critical area. I believe the book offers an excellent pathway towards this goal.' British Journal of Surgery

Review of first edition 'It is well written, with the correct balance of figures, tables and text, and also well referenced … I warmly recommend it.' Biomedical Sciences


A. Hughes, Phillip Chowienczyk, L. Poston, Kirsty M. McCulloch, J. C. McGrath, A. Halliday, M. Bennett, N. L. Occleston, P. T. Khaw, M. J. Caulfield, B. J. Hunt, J. M. Jurd, Patrick Vallance, Alan Moody, M. Schachter, Peter Weissberg, Janet Powell, John Tooke, Caroline Savage, T. Higgenbottam, M. Rose, L. Poston

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